Invention Grant
- Patent Title: Hepatitis B antiviral agents
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Application No.: US15152647Application Date: 2016-05-12
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Publication No.: US10738035B2Publication Date: 2020-08-11
- Inventor: Yao-Ling Qiu , Wei Li , Hui Cao , Meizhong Jin , Xuri Gao , Xiaowen Peng , Jorden Kass , Yat Sun Or
- Applicant: Enanta Pharmaceuticals, Inc.
- Applicant Address: US MA Watertown
- Assignee: Enanta Pharmaceuticals, Inc.
- Current Assignee: Enanta Pharmaceuticals, Inc.
- Current Assignee Address: US MA Watertown
- Agency: Elmore Patent Law Group, P.C.
- Agent Edgar W. Harlan; Carolyn S. Elmore
- Main IPC: C07D405/12
- IPC: C07D405/12 ; A61K31/454 ; A61K45/06 ; C07D231/38 ; C07D403/12 ; C07D211/46 ; A61K31/445 ; C07D401/14 ; C07D231/40 ; C07D401/12 ; A61K31/415 ; A61K31/4155 ; A61K31/5377 ; A61K31/4545

Abstract:
The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: X-A-Y—Z-L-R1 (I) which inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV life cycle of the hepatitis B virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HBV infection. The invention also relates to methods of treating an HBV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
Public/Granted literature
- US20160332996A1 Hepatitis B Antiviral Agents Public/Granted day:2016-11-17
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