A suturing system is provided. In an embodiment, the suturing system includes a sheath having a proximal end and a distal end. A needle is disposed distal the sheath in a pre-deployed configuration with a needle tip of the needle being orientated proximally towards the sheath. A body is disposed within the sheath, the body comprising a guide reducing an outer cross-sectional dimension of the body at the guide and forming a space between the body and the sheath, the guide being configured to receive the needle and direct the needle proximally toward the proximal end of the sheath. A suture is attached to the needle.