Systems and methods for a self-calibrating and self-adjusting network are disclosed. In one embodiment, a method is disclosed, comprising: obtaining a signal strength parameter for a mobile device at a base station; obtaining a position of the mobile device at the base station; and associating the position and the signal strength parameter in a database. The method may further comprise one or more of: adjusting transmission power for the mobile device at the base station based on the associated position and signal strength parameter; computing the position of the mobile device at the base station; calculating an average of the signal strength parameter over a time window, and storing the average associated with the position. The signal strength parameter may include at least one of a block error rate (BLER) and a radio signal strength indicator (RSSI), and the position may be a global positioning system (GPS) position.