A method, apparatus, and computer-readable medium at a transmitting network device or a target network device in a listen-before-talk (LBT) session that employ a spatial LBT procedure is disclosed. The spatial LBT procedure takes into account multiple-input multiple-output (MIMO) configuration information in measuring an effective interference. Accordingly, the spatial LBT procedure enables the transmitting network device or the target network device to more accurately measure an interference and make a more accurate decision on whether a channel is clear, and thus improves the system-wide performance. Also, the spatial LBT procedure allows the transmitting network device or the target/receiving network device to adaptively adjust the LBT power detection threshold when the MIMO configuration is not available. This also enables the network devices to more accurately measure interference and make a more accurate decision on whether the channel is clear, especially when advanced MIMO technologies are deployed in 5G or beyond.