Invention Grant
- Patent Title: Targeted shell for use in drug delivery system utilizing carbosilane dendrimer
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Application No.: US15991033Application Date: 2018-05-29
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Publication No.: US10772973B2Publication Date: 2020-09-15
- Inventor: Miho Suzuki , Ken Hatano , Shojiro Yoshida , Yasuhiro Yamashita
- Applicant: QUARRYMEN & Co. Inc. , Saitama University
- Applicant Address: JP Tokyo JP Saitama
- Assignee: QUARRYMEN & Co. Inc.,Saitama University
- Current Assignee: QUARRYMEN & Co. Inc.,Saitama University
- Current Assignee Address: JP Tokyo JP Saitama
- Agency: Locke Lord LLP
- Agent James E. Armstrong, IV; Nicholas J. DiCeglie, Jr.
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@ec5888e
- Main IPC: A61K47/69
- IPC: A61K47/69 ; A61K47/42 ; A61K49/00 ; A61K47/24 ; C07K17/00 ; A61K47/56 ; C08G83/00 ; A61K47/64 ; A61K47/66 ; A61K47/59 ; C07K14/435 ; A61P37/00 ; A61P35/00
Abstract:
The present invention is related to a targeted type shell for drug delivery system. The object of the present invention is to provide the targeted type shell for DDS, which comprises a carbosilane dendrimer containing a silole produced by which is formed by utilizing the reaction between thiol group and alkyl halide, and a targeted protein containing a labeled proteins such as green fluorescent protein with a target recognition site. The shell may incorporate compounds having a variety of molecular weight and biopolymers, and selectively deliver them into targeted cells.
Public/Granted literature
- US20180362718A1 Targeted Shell for Use in Drug Delivery System Utilizing Carbosilane Dendrimer Public/Granted day:2018-12-20
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