Invention Grant
- Patent Title: Antimicrobial peptidomimetics
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Application No.: US16038603Application Date: 2018-07-18
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Publication No.: US10787483B2Publication Date: 2020-09-29
- Inventor: Brian Cheng San Chia
- Applicant: Agency for Science, Technology and Research
- Applicant Address: SG Singapore
- Assignee: Agency for Science, Technology and Research
- Current Assignee: Agency for Science, Technology and Research
- Current Assignee Address: SG Singapore
- Agency: Choate, Hall & Stewart LLP
- Agent Brian E. Reese; Dana M. Daukss
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@6d809792 com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@31559ec6
- Main IPC: A61K38/06
- IPC: A61K38/06 ; C07K5/087 ; C07K5/117 ; C07K1/00 ; C07K1/06 ; C07K1/10 ; C07K5/02 ; C07K5/065 ; C07K5/072 ; A61K38/00

Abstract:
The present invention relates to peptidomimetics of the formula (I) or (I)c wherein L1, L2, L3, R1, R2, R3, R4, R5, R6, n, m, Q, X, Z1 and Z2 are defined as mentioned in the description and to salts and solvates of each of these compounds and to processes for the preparation thereof, compositions containing them and the uses of such compounds. It has been found that the compounds have a high microbicide activity and are suited to combat resistant bacteria, such as meticillin-resistant Staphylococcus aureus (MRSA) strains, at very low concentrations.
Public/Granted literature
- US20180354989A1 ANTIMICROBIAL PEPTIDOMIMETICS Public/Granted day:2018-12-13
Information query
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