Invention Grant
- Patent Title: Human PAC1 antibodies
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Application No.: US16572271Application Date: 2019-09-16
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Publication No.: US10793631B2Publication Date: 2020-10-06
- Inventor: Cen Xu , Agnes Eva Hamburger
- Applicant: AMGEN INC.
- Applicant Address: US CA Thousand Oaks
- Assignee: AMGEN INC.
- Current Assignee: AMGEN INC.
- Current Assignee Address: US CA Thousand Oaks
- Agent Angela L. Purcell
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K35/12 ; A61K39/00 ; A61P25/06

Abstract:
Antibodies and antigen-binding fragments thereof that bind to human PAC1 are provided. Nucleic acids encoding the antibodies and antigen-binding fragments thereof, vectors, and cells encoding the same are also provided. The antibodies and antigen-binding fragments thereof can inhibit binding of PAC1 to PACAP, and are useful in a number of PAC1 related disorders, including the treatment and/or prevention of headache disorders, including migraine and cluster headache.
Public/Granted literature
- US20200172614A1 HUMAN PAC1 ANTIBODIES Public/Granted day:2020-06-04
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