Invention Grant
- Patent Title: Electrochemical quantitation of autoantibodies
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Application No.: US15115033Application Date: 2015-01-29
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Publication No.: US10794852B2Publication Date: 2020-10-06
- Inventor: Robert L. Rubin , Konstantin N. Konstantinov , David A. Wall
- Applicant: STC.UNM , Robert L. Rubin , Konstantin N. Konstantinov , David A. Wall
- International Application: PCT/US2015/013434 WO 20150129
- International Announcement: WO2015/116769 WO 20150806
- Main IPC: G01N27/327
- IPC: G01N27/327 ; G01N33/543

Abstract:
This disclosure describes, in one aspect, a device for electrochemical quantitation of autoantibodies. Generally, the device includes a housing that defines a plurality of channels and at least two reaction zones. A first reaction zone includes a porous membrane and a first electrode assembly in fluid communication with a first channel. The first reaction zone also includes a first plurality of autoantigens immobilized to the porous membrane. The first electrode assembly is in communication with an amperometric reader. A second reaction zone includes a porous membrane and a second electrode assembly in fluid communication with a second channel. The second reaction zone includes a second plurality of autoantigens immobilized to the porous membrane. The second electrode assembly is in communication with the amperometric reader. Finally, the device includes a source of negative pressure in fluid communication with the first reaction zone and the second reaction zone.
Public/Granted literature
- US20160341687A1 ELECTROCHEMICAL QUANTITATION OF AUTOANTIBODIES Public/Granted day:2016-11-24
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