An example apparatus for supporting digital pre-distortion (DPD) and full duplex (FDX) in cable network environments is provided and includes a first path for signals being transmitted out of the apparatus, a second path for signals being received into the apparatus, a DPD actuator located on the first path, an amplifier located on the first path, an echo cancellation (EC) actuator located on the second path, and a data interface including a plurality of channels connecting the apparatus to a signal processor. DPD coefficients, EC coefficients and delay parameters are provided over the data interface from the signal processor to the apparatus. The DPD actuator predistorts signals on the first path using the DPD coefficients compensating for distortions introduced by the amplifier, and the EC actuator reduces interferences in signals on the second path using the EC coefficients and the delay parameters, facilitating FDX communication by the apparatus.