- 专利标题： Pertussis vaccines and methods of making and using
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申请号： US15474594申请日： 2017-03-30
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公开(公告)号： US10799573B2公开(公告)日： 2020-10-13
- 发明人: Timothy Joseph Brickman , Sandra Kay Armstrong
- 申请人： Regents of the University of Minnesota
- 申请人地址： US MN Minneapolis
- 专利权人： Regents of the University of Minnesota
- 当前专利权人： Regents of the University of Minnesota
- 当前专利权人地址： US MN Minneapolis
- 代理机构： Fish & Richardson P.C.
- 主分类号： A61K39/10
- IPC分类号： A61K39/10 ; A61K39/00 ; A61K39/02 ; C07K14/235 ; C12N1/20
摘要：
Bordetella pertussis iron receptor proteins or portions thereof (e.g., one or more extracellular domains), alone or spliced into B. pertussis scaffold proteins (e.g., fimbrial or flagellin), are provided and can be used in acellular vaccines to protect against pertussis or other Bordetella diseases in humans and non-human mammals. In addition, Bordetella species grown under iron-starved conditions are provided and can be used in whole cell vaccines to protect against pertussis or other Bordetella diseases in humans and non-human mammals.
公开/授权文献
- US20170333547A1 PERTUSSIS VACCINES AND METHODS OF MAKING AND USING 公开/授权日：2017-11-23
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