- 专利标题： Carbohydrate content of CTLA4 molecules
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申请号： US16044252申请日： 2018-07-24
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公开(公告)号： US10851150B2公开(公告)日： 2020-12-01
- 发明人: Kirk J. Leister , Eugene J. Schaefer , Ronald Charles Bates , Elizabeth A. Bramhall , David Michael Didio , Robert Donaldson , Alan R. Flesher , Helen Gray Haggerty , David Henry Kirkley , John Malcolm Tabor , Lee K. Tay , Pallaiah Thammana , Ajoy Velayudhan , David Edward Smolin , Reb J. Russell , Thomas James Vanden Boom , Dean Woodrow Brownell , Jeffrey Schrimsher , Joyce Patricia Whitehead
- 申请人： Bristol-Myers Squibb Company
- 申请人地址： US NJ Princeton
- 专利权人： Bristol-Myers Squibb Company
- 当前专利权人： Bristol-Myers Squibb Company
- 当前专利权人地址： US NJ Princeton
- 代理机构： Sterne, Kessler, Goldstein & Fox P.L.L.C.
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K14/705 ; A61K38/19 ; C07K16/28 ; A61K38/00 ; B01D15/38
摘要：
The invention provides for mammalian cells capable of producing recombinant CTLA4-Ig and variants thereof. The invention also provides for compositions comprising CTLA4-Ig and formulations thereof. The invention further provides for methods for mass-producing CTLA4-Ig from mammalian cells capable of producing this recombinant protein, and for purifying the CTLA4-Ig.
公开/授权文献
- US20200017569A9 CARBOHYDRATE CONTENT OF CTLA4 MOLECULES 公开/授权日：2020-01-16
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