The present disclosure relates to a pre-5th-Generation (5G) or 5G communication system to be provided for supporting higher data rates Beyond 4th-Generation (4G) communication system such as Long Term Evolution (LTE). An embodiment of the present disclosure relates to a method for operating a terminal, which includes receiving timing advance (TA) information related to an interference, determining whether to apply the TA information related to the interference, and transmitting uplink data based on the TA information related to the interference, and the terminal performing the same. Further, the present disclosure relates to a method and an apparatus for operating a base station operating with the terminal.