Some demonstrative embodiments include apparatuses, devices, systems and methods of communicating a Physical Layer Protocol Data Unit (PPDU). For example, an Enhanced Directional Multi-Gigabit (DMG) (EDMG) station (STA) may be configured to generate a Physical Layer (PHY) PPDU; generate one or more PPDU waveforms corresponding to one or more respective transmit chains for digital beamforming transmission of the PPDU; and transmit the PPDU via the one or more transmit chains over a channel bandwidth of at least 2.16 Gigahertz (GHz) in a frequency band above 45 GHz.