Embodiments are presented herein of apparatuses, systems, and methods for utilizing a flexible slot indicator in wireless communication. A base station (BS) may establish communication with a first user equipment device (UE). The BS may determine a transmission direction for each of a plurality of symbols included in one or more slots. The BS may transmit a slot format indicator (SFI) to the UE. The SFI may indicate the transmission direction for each of the plurality of symbols included in one or more slots. The BS and the UE may perform communication during the one or more slots according to the determined transmission direction.