Invention Grant
- Patent Title: Oral pH independent dosage formulation for treating neurodegenerative disorders
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Application No.: US16446634Application Date: 2019-06-20
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Publication No.: US10894023B2Publication Date: 2021-01-19
- Inventor: Meng-Ju Lee , Shu-Hsien Chang , Chih-Chiang Yang , Yuan-Chih Le , Tse-Ching Lin , Ko-Chiang Chen , Lai-Cheng Chin , Tai-Yin Ke , Pei-Ying Liao
- Applicant: Center Laboratories, Inc. , Medical and Pharmaceutical Industry Technology and Development Center
- Applicant Address: TW Taipei; TW New Taipei
- Assignee: Center Laboratories, Inc.,Medical and Pharmaceutical Industry Technology and Development Center
- Current Assignee: Center Laboratories, Inc.,Medical and Pharmaceutical Industry Technology and Development Center
- Current Assignee Address: TW Taipei; TW New Taipei
- Main IPC: A61K31/13
- IPC: A61K31/13 ; A61K31/445 ; A61K9/16 ; A61K9/50 ; A61K9/48 ; A61K9/00 ; A61P25/16 ; A61P25/14 ; A61P25/28
Abstract:
Disclosed herein is an oral dosage formulation suitable for treating a neurodegenerative disorder. The oral dosage formulation contains both sustained-release and immediate-release drugs. The sustained-release drug in the oral dosage formulation is memantine, and the immediate-release drug in the oral dosage formulation is donepezil and/or memantine, and the formulation is characterized in having a pH-independent dissolution profile of memantine at a pH range from about 1.0 to about 7.0.
Public/Granted literature
- US20190388340A1 ORAL pH INDEPENDENT DOSAGE FORMULATION FOR TREATING NEURODEGENERATIVE DISORDERS Public/Granted day:2019-12-26
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