An information processing apparatus includes: an obtaining unit configured to obtain a manually-taken object image group, the manually-taken object image group including a plurality of object images, the plurality of object images being generated by taking images of an object while moving a focal position of an image pickup device manually; a first calculator capable of calculating, based on pieces of contrast information on the plurality of object images in the obtained manually-taken object image group, a first in-focus position of the image pickup device relative to the object by performing fitting using a predetermined function; and a driver capable of moving, based on an autofocus instruction input by a user, the focal position of the image pickup device to the calculated first in-focus position.