Invention Grant
- Patent Title: Combination therapy with an anti-HER2 antibody-drug conjugate and a Bcl-2 inhibitor
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Application No.: US15849018Application Date: 2017-12-20
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Publication No.: US10898570B2Publication Date: 2021-01-26
- Inventor: Gail Lewis Phillips , Deepak Sampath , Ingrid Wertz
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Baker Botts L.L.P.
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/32 ; G01N33/574 ; A61K47/68 ; A61K31/635 ; A61K45/06 ; A61P35/00 ; A61K31/496 ; A61K39/00
Abstract:
The present invention is directed to a combination therapy involving an anti-HER2 antibody-drug conjugate and a selective Bcl-2 inhibitor for the treatment of a patient suffering from cancer, particularly, a HER2-expressing cancer.
Public/Granted literature
- US20180140700A1 COMBINATION THERAPY WITH AN ANTI-HER2 ANTIBODY-DRUG CONJUGATE AND A BCL-2 INHIBITOR Public/Granted day:2018-05-24
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