- 专利标题: Vinylogous phenethylamines as neurotransmitter releasers
-
申请号: US16300436申请日: 2017-05-11
-
公开(公告)号: US10899699B2公开(公告)日: 2021-01-26
- 发明人: Bruce Blough , Ann Decker , Richard Rothman
- 申请人: RESEARCH TRIANGLE INSTITUTE
- 申请人地址: US NC Research Triangle Park
- 专利权人: RESEARCH TRIANGLE INSTITUTE
- 当前专利权人: RESEARCH TRIANGLE INSTITUTE
- 当前专利权人地址: US NC Research Triangle Park
- 代理机构: Hultquist, PLLC
- 代理商 Steven J. Hultquist
- 国际申请: PCT/US2017/032143 WO 20170511
- 国际公布: WO2017/197101 WO 20171116
- 主分类号: A61K31/135
- IPC分类号: A61K31/135 ; A61P25/30 ; C07C211/28
摘要:
The disclosure provides monoamine neurotransmitter releaser and/or monoamine uptake inhibitor compounds having biogenic amine transporter activity but lacking substantial activity at 5-HT2 receptor subtypes. The phenethylamine or vinylogous phenethylamine compounds of the disclosure are useful in treating diseases, conditions and/or disorders mediated by activity of one or more of the monoamine neurotransmitters.
公开/授权文献
- US20190225573A1 VINYLOGOUS PHENETHYLAMINES AS NEUROTRANSMITTER RELEASERS 公开/授权日:2019-07-25
信息查询