Invention Grant
- Patent Title: Methods for preparing botanical extracts
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Application No.: US16514337Application Date: 2019-07-17
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Publication No.: US10912812B2Publication Date: 2021-02-09
- Inventor: Kristen Huber , Michael Voronkov , Jose Fernandez , Karl Rouzard , Eduardo Perez , Maxwell Stock , Jeffry Stock
- Applicant: Signum Biosciences, Inc.
- Applicant Address: US NJ Monmouth Junction
- Assignee: Signum Biosciences, Inc.
- Current Assignee: Signum Biosciences, Inc.
- Current Assignee Address: US NJ Monmouth Junction
- Agency: Kim IP Law Group LLC
- Main IPC: A61K8/97
- IPC: A61K8/97 ; A61K36/9066 ; A61K36/77 ; A61K36/87 ; A61K36/33 ; A61K36/73 ; A61K45/06 ; A61K9/00 ; A61K36/14 ; A61K36/185 ; A61K36/23 ; A61K36/235 ; A61K36/28 ; A61K36/31 ; A61K36/45 ; A61K36/52 ; A61K36/54 ; A61K36/575 ; A61K36/71 ; A61K36/736 ; A61K36/79 ; A61Q19/08

Abstract:
Method of preparing a botanical extract that includes contacting a raw botanical with a solvent having a dielectric constant ranging from about 2.3 to about 25 and allowing the mixture to reside for a sufficient time to obtain a crude extract; filtering out remaining raw botanical and evaporating the solvent from the crude extract under reduced pressure to obtain a dried crude extract; washing the dried crude extract with a polar solvent having a dielectric constant of no less than 30, heating the resulting mixture, and allowing to cool to ambient; collecting a filtrate from the above cooled mixture; washing the collected filtrate with a non-polar solvent having a dielectric constant of no more than 2.0; and filtering and drying the mixture to obtain the botanical extract.
Public/Granted literature
- US20190336561A1 Compositions for Inhibiting PP2A Demethylation Public/Granted day:2019-11-07
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