Invention Grant
- Patent Title: Monoclonal antibody inhibitor of factor XIIA
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Application No.: US15746048Application Date: 2016-07-21
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Publication No.: US10913802B2Publication Date: 2021-02-09
- Inventor: Shauna Mason , Jon A. Kenniston , Andrew Nixon , Daniel J. Sexton , Stephen R. Comeau , Burt Adelman
- Applicant: Dyax Corp.
- Applicant Address: US MA Lexington
- Assignee: Dyax Corp.
- Current Assignee: Dyax Corp.
- Current Assignee Address: US MA Lexington
- Agency: Wolf, Greenfield & Sacks, P.C.
- International Application: PCT/US2016/043265 WO 20160721
- International Announcement: WO2017/015431 WO 20170126
- Main IPC: C07K16/36
- IPC: C07K16/36 ; A61K39/00 ; A61P7/02 ; A61P9/00 ; A61P11/00

Abstract:
Disclosed herein are anti-Factor XIIa antibodies and methods of using such for treating diseases associated with Factor XII, including diseases associated with contact system activation, plasma prekallikrein signaling (e.g., hereditary angioedema), and ocular diseases.
Public/Granted literature
- US20190002584A1 A MONOCLONAL ANTIBODY INHIBITOR OF FACTOR XIIA Public/Granted day:2019-01-03
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