Methods and apparatus for distribution and execution of instructions in a distributed computing environment are disclosed. An example method includes requesting, by executing an instruction with a processor within a deployment environment, a package supporting execution of a second instruction from a management endpoint, loading, by executing an instruction with the processor, a first component of the package in a command cache, the first component including a third instruction to implement a plugin framework, causing, by executing an instruction with the processor, a second component of the package to be stored in an instruction cache, the instruction cache located outside the deployment environment, the second component including a fourth instruction, and executing the first component from the command cache.