- 专利标题： Protein tyrosine phosphatase inhibitors and methods of use thereof
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申请号： US17025644申请日： 2020-09-18
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公开(公告)号： US10954202B2公开(公告)日： 2021-03-23
- 发明人: Zhaoming Xiong , Jennifer M. Frost , Philip R. Kym , Xueqing Wang , Shuang Chen , Dennie Welch
- 申请人： Calico Life Sciences LLC , AbbVie Inc.
- 申请人地址： US CA South San Francisco; US IL North Chicago
- 专利权人： Calico Life Sciences LLC,AbbVie Inc.
- 当前专利权人： Calico Life Sciences LLC,AbbVie Inc.
- 当前专利权人地址： US CA South San Francisco; US IL North Chicago
- 代理机构： Goodwin Procter LLP
- 主分类号： C07D285/10
- IPC分类号： C07D285/10
摘要：
Provided herein are compounds, compositions, and methods useful for inhibiting protein tyrosine phosphatase, e.g., protein tyrosine phosphatase non-receptor type 2 (PTPN2) and/or protein tyrosine phosphatase non-receptor type 1 (PTPN1), and for treating related diseases, disorders and conditions favorably responsive to PTPN1 or PTPN2 inhibitor treatment, e.g., a cancer or a metabolic disease.
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