A mechanical seal arrangement includes a first mechanical seal with a rotating slide ring and a stationary slide ring, which define a sealing gap in between them. The mechanical seal arrangement includes a first sealing space that is filled with a sealing liquid. The first mechanical seal seals off the sealing space against a surrounding area, a first piston arrangement with a piston element and flexible wall areas that define a first piston interior space, wherein the first piston interior space is in fluid connection with the first sealing space. A piston outer surface of the piston element is in fluid connection with the surrounding area, and a first pre-stressing appliance that exerts a first preload force (F1) on the piston element of the first piston arrangement.