- Patent Title: Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
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Application No.: US16555634Application Date: 2019-08-29
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Publication No.: US10959986B2Publication Date: 2021-03-30
- Inventor: James Aaron Balog , Steven P. Seitz , Susheel Jethanand Nara , Saumya Roy , Srinivasan Thangathirupathy , Soodamani Thangavel , Ramesh Kumar Sistla
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee Address: US NJ Princeton
- Agency: BakerHostetler
- Main IPC: A61K31/415
- IPC: A61K31/415 ; A61K31/5377 ; C07D231/12 ; C07D401/12 ; C07D403/12 ; C07D261/08 ; C07D277/22 ; C07D285/08 ; C07D211/60 ; C07D317/50 ; C07D307/36 ; C07D333/54 ; C07D231/56 ; C07D221/22 ; C07D471/04 ; C07D487/04 ; A61K31/17 ; A61K31/4439 ; A61K31/506 ; A61K31/42 ; A61K31/426 ; A61K31/433 ; A61K31/357 ; A61K31/341 ; A61K31/381 ; C07C275/42
Abstract:
There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or inflammatory disorders utilizing the compounds of the disclosure.
Public/Granted literature
- US20200069646A1 INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF THEIR USE Public/Granted day:2020-03-05
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