- 专利标题: Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
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申请号: US16555634申请日: 2019-08-29
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公开(公告)号: US10959986B2公开(公告)日: 2021-03-30
- 发明人: James Aaron Balog , Steven P. Seitz , Susheel Jethanand Nara , Saumya Roy , Srinivasan Thangathirupathy , Soodamani Thangavel , Ramesh Kumar Sistla
- 申请人: BRISTOL-MYERS SQUIBB COMPANY
- 申请人地址: US NJ Princeton
- 专利权人: BRISTOL-MYERS SQUIBB COMPANY
- 当前专利权人: BRISTOL-MYERS SQUIBB COMPANY
- 当前专利权人地址: US NJ Princeton
- 代理机构: BakerHostetler
- 主分类号: A61K31/415
- IPC分类号: A61K31/415 ; A61K31/5377 ; C07D231/12 ; C07D401/12 ; C07D403/12 ; C07D261/08 ; C07D277/22 ; C07D285/08 ; C07D211/60 ; C07D317/50 ; C07D307/36 ; C07D333/54 ; C07D231/56 ; C07D221/22 ; C07D471/04 ; C07D487/04 ; A61K31/17 ; A61K31/4439 ; A61K31/506 ; A61K31/42 ; A61K31/426 ; A61K31/433 ; A61K31/357 ; A61K31/341 ; A61K31/381 ; C07C275/42
摘要:
There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or inflammatory disorders utilizing the compounds of the disclosure.
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