发明授权
- 专利标题： Pyrrolotriazinones and imidazotriazinones as ubiquitin-specific protease 7 inhibitors
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申请号： US16449599申请日： 2019-06-24
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公开(公告)号： US10981915B2公开(公告)日： 2021-04-20
- 发明人: Stephanos Ioannidis , Adam Charles Talbot , Bruce Follows , Alexandre Joseph Buckmelter , Minghua Wang , Ann-Marie Campbell
- 申请人： Valo Early Discovery, Inc.
- 申请人地址： US MA Boston
- 专利权人： Valo Early Discovery, Inc.
- 当前专利权人： Valo Early Discovery, Inc.
- 当前专利权人地址： US MA Boston
- 代理机构： Choate, Hall & Stewart LLP
- 代理商 Michael A. Shinall; Nicholas J. Pace
- 主分类号： C07D487/04
- IPC分类号： C07D487/04
摘要：
The invention relates to inhibitors of USP7 inhibitors useful in the treatment of cancers, neurodegenerative diseases, immunological disorders, inflammatory disorders, cardiovascular diseases, ischemic diseases, viral infections and diseases, and bacterial infections and diseases, having the Formula: where R1, R2, R3, R4, R5, R5′, R6, X1, X2, m, and n are described herein.
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