Invention Grant
- Patent Title: Activating pyruvate kinase R and mutants thereof
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Application No.: US16575456Application Date: 2019-09-19
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Publication No.: US11001588B2Publication Date: 2021-05-11
- Inventor: David R. Lancia, Jr. , Gary Gustafson , Neal Green , Lorna Mitchell , Anna Ericsson , David Richard
- Applicant: FORMA Therapeutics, Inc.
- Applicant Address: US MA Watertown
- Assignee: FORMA Therapeutics, Inc.
- Current Assignee: FORMA Therapeutics, Inc.
- Current Assignee Address: US MA Watertown
- Agency: Barnes & Thornburg LLP
- Main IPC: C07D401/14
- IPC: C07D401/14 ; A61K31/4439 ; C07D487/04 ; A61K9/00
Abstract:
The disclosure provides chemical compounds useful as activators of PKR. PKR activating compounds are useful in the treatment of disease and disorders associated with modulation of PKR and/or PKM2, such as pyruvate kinase deficiency (PKD).
Public/Granted literature
- US20200087309A1 ACTIVATING PYRUVATE KINASE R AND MUTANTS THEREOF Public/Granted day:2020-03-19
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