A method for preparing titanium dioxide-based synthetic paper capable of degrading organic pollutants, including: adding thermoplastic polyurethane particles and N,N-dimethylformamide or N,N-dimethylacetamide in a reactor, heating, and stirring to fully dissolve the thermoplastic polyurethane particles in a solvent to obtain a polyurethane solution; adding titanium dioxide powder having photocatalytic degradation property in the polyurethane solution, stirring uniformly to obtain a solid-liquid mixture, and standing for defoaming; uniformly coating the solid-liquid mixture onto a piece of release paper, soaking the release paper coated with the solid-liquid mixture into an aqueous solution of sliver nitrate having photocatalytic degradation property, completely curing the solid-liquid mixture to form a film, and soaking the release paper and the film into an aqueous solution of sodium chloride; drying, cooling, removing the release paper, and cutting the film to a proper size to obtain the titanium dioxide-based synthetic paper.