Invention Grant
- Patent Title: Bile acid derivatives as FXR/TGR5 agonists and methods of use thereof
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Application No.: US16593262Application Date: 2019-10-04
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Publication No.: US11040998B2Publication Date: 2021-06-22
- Inventor: Guoqiang Wang , Yat Sun Or , Ruichao Shen , Xuechao Xing , Jiang Long , Peng Dai , Brett Granger , Jing He
- Applicant: ENANTA PHARMACEUTICALS, INC.
- Applicant Address: US MA Watertown
- Assignee: ENANTA PHARMACEUTICALS, INC.
- Current Assignee: ENANTA PHARMACEUTICALS, INC.
- Current Assignee Address: US MA Watertown
- Agency: Elmore Patent Law Group, P.C.
- Agent Edgar W. Harlan; Carolyn S. Elmore
- Main IPC: C07J43/00
- IPC: C07J43/00 ; C07J41/00 ; C07J9/00 ; C07J51/00
Abstract:
The present invention provides compounds represented by Formula I, or pharmaceutically acceptable salts, stereoisomers, solvates, hydrates or combination thereof, The invention also provides pharmaceutical compositions comprising these compounds and methods of using this compounds for treating FXR-mediated or TGR5-mediated diseases or conditions.
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