Invention Grant
- Patent Title: KRAS G12C inhibitors and methods of using the same
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Application No.: US16687546Application Date: 2019-11-18
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Publication No.: US11053226B2Publication Date: 2021-07-06
- Inventor: Youngsook Shin , Victor J. Cee , Christopher M. Tegley , Brian Alan Lanman , Ryan Paul Wurz , Kevin C. Yang , Vu Van Ma , Daniel Erlanson , Joon Won Jeong , Raymond V. Fucini , Jeffrey Iwig
- Applicant: Amgen Inc.
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agent Markus Bergauer
- Main IPC: C07D403/14
- IPC: C07D403/14 ; C07D401/14 ; C07D403/12 ; C07D417/14 ; C07D471/04 ; C07D487/04 ; C07D498/04 ; A61P35/00

Abstract:
Provided herein are KRAS G12C inhibitors, composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.
Public/Granted literature
- US20200165231A1 KRAS G12C INHIBITORS AND METHODS OF USING THE SAME Public/Granted day:2020-05-28
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