发明授权
- 专利标题: BCKDK inhibitors
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申请号: US17078257申请日: 2020-10-23
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公开(公告)号: US11059833B2公开(公告)日: 2021-07-13
- 发明人: Samit Kumar Bhattacharya , Leanne Marie Buzon , Kevin James Filipski , David Andrew Griffith , Bethany Lyn Kormos , Luis Angel Martinez-Alsina , Russell Alan Miller , Matthew Richard Reese , Rachel Jane Roth Flach , Yuan Zhang
- 申请人: Pfizer Inc.
- 申请人地址: US NY New York
- 专利权人: Pfizer Inc.
- 当前专利权人: Pfizer Inc.
- 当前专利权人地址: US NY New York
- 代理商 Lisa A. Samuels
- 主分类号: C07D495/04
- IPC分类号: C07D495/04 ; A61K31/155 ; A61K31/4985 ; A61K31/7048 ; A61K45/06
摘要:
Described herein are compounds of Formula I, wherein R1, R2, and R3 are defined herein, their use as branched-chain alpha keto acid dehydrogenase kinase inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to treat, for example, diabetes, NASH and heart failure.
公开/授权文献
- US20210087204A1 BCKDK INHIBITORS 公开/授权日:2021-03-25
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