A signal processing method and apparatus, a device, and a computer readable storage medium are provided, which relate to the field of communication technology, to reduce collisions of physical broadcast channel (PBCH) demodulation reference signals (DMRSs). The signal processing method provided by embodiments of the present disclosure includes: generating a plurality of candidate PBCH DMRS sequences; acquiring a mapping relationship between PBCH DMRS sequences and resource element (RE) groups; and transmitting the candidate PBCH DMRS sequences by using RE groups corresponding to the candidate PBCH DMRS sequences according to the mapping relationship. Therefore, the embodiments of the present disclosure may reduce collisions of PBCH DMRSs.