Invention Grant
- Patent Title: Method for producing pyrrole compound
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Application No.: US16739707Application Date: 2020-01-10
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Publication No.: US11066362B2Publication Date: 2021-07-20
- Inventor: Takashi Ouchi , Giho Goh , Sunmi Kim , Jinsoon Choi , Hunsoo Park
- Applicant: Takeda Pharmaceutical Company Limited
- Applicant Address: JP Osaka
- Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee Address: JP Osaka
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- Agent David G. Conlin; Joohee Lee
- Priority: JPJP2015-131610 20150630
- Main IPC: C07D207/36
- IPC: C07D207/36 ; C07D207/34 ; B01J23/44 ; C07B61/00 ; C07C253/30 ; C07C255/42 ; C07D401/12 ; B01J8/02 ; B01J21/04 ; B01J29/08 ; C07B31/00 ; C07B41/06 ; C07C255/28

Abstract:
The present invention provides a production method of a 3-cyanopyrrole compound possibly useful as an intermediate for pharmaceutical products. A production method of compound (II) including subjecting compound (I) to a reduction reaction, in which the aforementioned reduction reaction is continuous hydrogenation reaction in a fixed bed reactor filled with a supported metal catalyst. A production method of compound (III) including subjecting compound (I) to a reduction reaction followed by a cyclization reaction, in which the aforementioned reduction reaction is continuous hydrogenation reaction in a fixed bed reactor filled with a supported metal catalyst.
Public/Granted literature
- US20200148637A1 METHOD FOR PRODUCING PYRROLE COMPOUND Public/Granted day:2020-05-14
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