A solution for selecting an optimal user Plane entity (with Control and User Plane Separation (CUPS)) per UE during seamless roaming. In one embodiment, a method is provide that is performed by a control plane entity in a mobile core network that supports inter public land mobile network (PLMN) roaming among two or more PLMNs. The method includes obtaining a create session request from an entity in a second PLMN to which a user equipment has roamed from a first PLMN; selecting a particular user plane entity among a plurality of user plane entities based on one or more user equipment related parameters; and establishing a session with the particular user plane entity to serve user plane traffic in the mobile core network for the user equipment.