An uplink power control method and a communications device are described. The method includes receiving, by a terminal device, power control indication information sent by a network device. The power control indication information indicates a first power offset set, and the first power offset set is any one of at least two power offset sets. The method further includes receiving, by the terminal device, a transmit power control (TPC) command sent by the network device. The TPC indicates a first offset in the first power offset set. The method includes determining, by the terminal device, uplink transmit power based on the first offset. Impact of cross interference is considered in determining the uplink transmit power. Thus, the method can meet requirements of future mobile communications and improve system performance.