- 专利标题： Compositions and methods for treating cancer with anti-CD38 immunotherapy
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申请号： US16698186申请日： 2019-11-27
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公开(公告)号： US11103533B2公开(公告)日： 2021-08-31
- 发明人: Dina Schneider , Rimas J. Orentas , Boro Dropulic , Dimiter S. Dimitrov , Zhongyu Zhu
- 申请人： Lentigen Technology, Inc. , The U.S.A., as represented by the Secretary, Department of Health and Human Services
- 申请人地址： US MD Gaithersburg; US MD Bethesda
- 专利权人： Lentigen Technology, Inc.,The U.S.A., as represented by the Secretary, Department of Health and Human Services
- 当前专利权人： Lentigen Technology, Inc.,The U.S.A., as represented by the Secretary, Department of Health and Human Services
- 当前专利权人地址： US MD Gaithersburg; US MD Bethesda
- 代理机构： Fish & Richardson P.C.
- 代理商 Serge Sira, Esq.; Gregory J. Hwa, Esq.
- 主分类号： A61K35/17
- IPC分类号： A61K35/17 ; A61K39/00 ; A61P35/02 ; C07K16/28 ; C12N15/86
摘要：
Chimeric antigen receptors containing CD38 antigen binding domains are disclosed. Nucleic acids, recombinant expression vectors, host cells, antigen binding fragments, and pharmaceutical compositions, relating to the chimeric antigen receptors are also disclosed. Methods of treating or preventing cancer in a subject, and methods of making chimeric antigen receptor T cells are also disclosed.
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