Invention Grant
- Patent Title: Small molecule androgen receptor inhibitors and methods of use thereof
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Application No.: US16661510Application Date: 2019-10-23
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Publication No.: US11104646B2Publication Date: 2021-08-31
- Inventor: Milton L. Brown , Shujie Hou , Partha Banerjee , Karishma Amin
- Applicant: GEORGETOWN UNIVERSITY
- Applicant Address: US DC Washington
- Assignee: GEORGETOWN UNIVERSITY
- Current Assignee: GEORGETOWN UNIVERSITY
- Current Assignee Address: US DC Washington
- Agency: Kilpatrick Townsend & Stockton LLP
- Main IPC: C07D209/88
- IPC: C07D209/88 ; A61K45/06 ; A61P35/00 ; A61K31/403
Abstract:
Small molecule carbazole compounds for use as androgen receptor inhibitors are provided herein. Also provided herein are methods for using the carbazole compounds in treating prostate cancer, including castration-resistant prostate cancer and enzalutamide-resistant prostate cancer. The methods include administering to a subject an effective amount of a compound or composition as described herein.
Public/Granted literature
- US20200247751A1 SMALL MOLECULE ANDROGEN RECEPTOR INHIBITORS AND METHODS OF USE THEREOF Public/Granted day:2020-08-06
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