Systems, devices, and methods related to a Deep Learning Accelerator and memory are described. For example, a microphone may be configured to execute instructions with matrix operands and configured with: a transducer to convert sound waves to electrical signals; an analog to digital converter to generate audio data according to the electrical signals; random access memory to store instructions executable by the Deep Learning Accelerator and store matrices of an Artificial Neural Network; and a controller to store the audio data in the random access memory as an input to the Artificial Neural Network. The Deep Learning Accelerator can execute the instructions to generate an output of the Artificial Neural Network, which may be provided as the primary output of the microphone to a computer system, such as a voice-based digital assistant.