- 专利标题： Method and composition to improve absorption of therapeutic agents
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申请号： US12387977申请日： 2009-05-11
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公开(公告)号： US11135188B2公开(公告)日： 2021-10-05
- 发明人: Eric R. First , Ashish B. Patel , Guido Schmitz , Stephanie Petaway-Hickson , Hung-Huar Tong
- 申请人： Eric R. First , Ashish B. Patel , Guido Schmitz , Stephanie Petaway-Hickson , Hung-Huar Tong
- 申请人地址： US NJ Morristown; US NJ West Orange; US NJ Sparta; US NJ Morris Plains; US NJ Basking Ridge
- 专利权人： Eric R. First,Ashish B. Patel,Guido Schmitz,Stephanie Petaway-Hickson,Hung-Huar Tong
- 当前专利权人： Eric R. First,Ashish B. Patel,Guido Schmitz,Stephanie Petaway-Hickson,Hung-Huar Tong
- 当前专利权人地址： US NJ Morristown; US NJ West Orange; US NJ Sparta; US NJ Morris Plains; US NJ Basking Ridge
- 主分类号： A61K31/192
- IPC分类号： A61K31/192 ; A61K9/20 ; A61K31/167 ; A61K9/14
摘要：
A tablet with an enhanced dissolution profile for a medicinally active ingredient such as aspirin and methods for making the tablet. The tablet comprises a blend of crystals of the medicinally active ingredient and a dissolution aid such as sodium or calcium carbonate or bicarbonate that coats the crystals upon co-milling. The blend is then compressed to form tablets that have an enhanced dissolution profile for the medicinally active ingredient.
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