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公开(公告)号:US08323688B2
公开(公告)日:2012-12-04
申请号:US12377401
申请日:2007-08-28
IPC分类号: A61K38/27 , A61K9/20 , A61P5/06 , C07C229/00
CPC分类号: A61K45/06 , A61K9/19 , A61K9/2027 , A61K9/2054 , A61K9/4866 , A61K31/198 , A61K38/27
摘要: The present invention relates to dosage forms of human growth hormone, the use of an absorption enhancer to allow absorption of human growth hormone into the systemic circulation in a biologically active form, in particular after oral administration, as well as the use of oral dosage forms comprising human growth hormone and an absorption enhancer for the treatment of human growth hormone deficiencies and disorders associated therewith.
摘要翻译: 本发明涉及人生长激素的剂型,使用吸收促进剂以允许以生物活性形式,特别是口服给药后将人生长激素吸收到全身循环中,以及使用口服剂型 包括人生长激素和用于治疗与其相关的人生长激素缺乏和紊乱的吸收增强剂。
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公开(公告)号:US20120244218A1
公开(公告)日:2012-09-27
申请号:US13065643
申请日:2011-03-25
申请人: Shane E. Durkee , Pradnya Beke , Eric R. First , Ashish B. Patel
发明人: Shane E. Durkee , Pradnya Beke , Eric R. First , Ashish B. Patel
CPC分类号: A61K9/4866 , A61K9/2054 , A61K31/194 , A61K33/06 , A61K33/10
摘要: An oral dosage form for administration to an animal comprising a biologically utilizable form of calcium and a extended release system that maintains the calcium level in the animal's bloodstream at a substantially beneficial level for a defined period of time.
摘要翻译: 一种用于给予动物的口服剂型,其包含生物可利用形式的钙和延长释放系统,其将动物血液中的钙水平维持在确定的时间段内基本上有益的水平。
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公开(公告)号:USD627078S1
公开(公告)日:2010-11-09
申请号:US29357707
申请日:2010-03-16
申请人: Atsushi Matsuo , James McCay , Ashish B. Patel , Eric R. First
设计人: Atsushi Matsuo , James McCay , Ashish B. Patel , Eric R. First
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公开(公告)号:US20100247608A1
公开(公告)日:2010-09-30
申请号:US12377401
申请日:2007-08-28
CPC分类号: A61K45/06 , A61K9/19 , A61K9/2027 , A61K9/2054 , A61K9/4866 , A61K31/198 , A61K38/27
摘要: The present invention relates to dosage forms of human growth hormone, the use of an absorption enhancer to allow absorption of human growth hormone into the systemic circulation in a biologically active form, in particular after oral administration, as well as the use of oral dosage forms comprising human growth hormone and an absorption enhancer for the treatment of human growth hormone deficiencies and disorders associated therewith.
摘要翻译: 本发明涉及人生长激素的剂型,使用吸收促进剂以允许以生物活性形式,特别是口服给药后将人生长激素吸收到全身循环中,以及使用口服剂型 包括人生长激素和用于治疗与其相关的人生长激素缺乏和紊乱的吸收增强剂。
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公开(公告)号:US11135188B2
公开(公告)日:2021-10-05
申请号:US12387977
申请日:2009-05-11
IPC分类号: A61K31/192 , A61K9/20 , A61K31/167 , A61K9/14
摘要: A tablet with an enhanced dissolution profile for a medicinally active ingredient such as aspirin and methods for making the tablet. The tablet comprises a blend of crystals of the medicinally active ingredient and a dissolution aid such as sodium or calcium carbonate or bicarbonate that coats the crystals upon co-milling. The blend is then compressed to form tablets that have an enhanced dissolution profile for the medicinally active ingredient.
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公开(公告)号:USD630759S1
公开(公告)日:2011-01-11
申请号:US29357708
申请日:2010-03-16
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7.
公开(公告)号:US20130122098A1
公开(公告)日:2013-05-16
申请号:US13373410
申请日:2011-11-14
IPC分类号: A61K9/14 , A61P25/04 , A61K31/60 , A61P29/00 , A61K31/5513 , A61K31/485
CPC分类号: A61K9/143 , A61K9/2027 , A61K9/2054 , A61K9/2095 , A61K31/485 , A61K31/5513 , A61K31/60
摘要: A tablet with an enhanced dissolution profile for a medicinally active ingredient such as aspirin and methods for making the tablet. The tablet comprises a blend of crystals of the medicinally active ingredient and a dissolution aid such as sodium or calcium carbonate or bicarbonate that coats the crystals upon co-milling. The blend is then compressed to form tablets that have an enhanced dissolution profile for the medicinally active ingredient.
摘要翻译: 具有增强的药物活性成分(例如阿司匹林)的溶出曲线的片剂和制备片剂的方法。 片剂包含药物活性成分的结晶和溶解助剂例如碳酸钙或碳酸氢钙的混合物,其在共研磨时涂覆晶体。 然后将共混物压制成具有药物活性成分的增强的溶出曲线的片剂。
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公开(公告)号:USD627896S1
公开(公告)日:2010-11-23
申请号:US29357618
申请日:2010-03-15
申请人: Atsushi Matsuo , Jonathan Lee , James McCay , Ashish B. Patel , Eric R. First
设计人: Atsushi Matsuo , Jonathan Lee , James McCay , Ashish B. Patel , Eric R. First
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9.
公开(公告)号:US20100286100A1
公开(公告)日:2010-11-11
申请号:US12387977
申请日:2009-05-11
IPC分类号: A61K31/60 , A61K31/167 , A61K31/192
CPC分类号: A61K31/192 , A61K9/143 , A61K9/2009 , A61K31/167
摘要: A tablet with an enhanced dissolution profile for a medicinally active ingredient such as aspirin and methods for making the tablet. The tablet comprises a blend of crystals of the medicinally active ingredient and a dissolution aid such as sodium or calcium carbonate or bicarbonate that coats the crystals upon co-milling. The blend is then compressed to form tablets that have an enhanced dissolution profile for the medicinally active ingredient.
摘要翻译: 具有增强的药物活性成分(例如阿司匹林)的溶出曲线的片剂和制备片剂的方法。 片剂包含药物活性成分的结晶和溶解助剂例如碳酸钙或碳酸氢钙的混合物,其在共研磨时涂覆晶体。 然后将共混物压制成具有药物活性成分的增强的溶出曲线的片剂。
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