Invention Grant
- Patent Title: Antibodies to alpha-synuclein and uses thereof
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Application No.: US16486238Application Date: 2018-02-16
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Publication No.: US11142570B2Publication Date: 2021-10-12
- Inventor: Michael K. Ahlijanian , Jere Ernest Meredith, Jr. , Nino Devidze , John David Graef , Edward L. Halk
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee Address: US NJ Princeton
- Agency: Nelson Mullins Riley & Scarborough LLP
- Agent Jane E. Remillard, Esq.; Jill Gorny Sloper, Esq.
- International Application: PCT/US2018/000032 WO 20180216
- International Announcement: WO2018/151821 WO 20180823
- Main IPC: C07K16/18
- IPC: C07K16/18 ; A61K39/395
Abstract:
Disclosed herein are anti-α-synuclein antibodies which preferentially bind to oligomeric α-synuclein over monomeric α-synuclein, therapeutic compositions comprising the antibodies, and methods of using the antibodies to treat synucleinopathies.
Public/Granted literature
- US20200231661A1 ANTIBODIES TO ALPHA-SYNUCLEIN AND USES THEREOF Public/Granted day:2020-07-23
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