Invention Grant
- Patent Title: Dimethyl-nonatetraenyl-trimethyl-cyclohexyl compounds and uses thereof
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Application No.: US15987274Application Date: 2018-05-23
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Publication No.: US11148998B2Publication Date: 2021-10-19
- Inventor: James Varani , Hollis Showalter , Andy White , Kent J. Johnson
- Applicant: The Regents of the University of Michigan
- Applicant Address: US MI Ann Arbor
- Assignee: The Regents of the University of Michigan
- Current Assignee: The Regents of the University of Michigan
- Current Assignee Address: US MI Ann Arbor
- Agency: Casimir Jones, S.C.
- Agent Robert A. Goetz
- Main IPC: A61K45/06
- IPC: A61K45/06 ; C07C235/30 ; C07D209/54 ; C07D305/06 ; C07C233/50 ; C07C233/31 ; C07D211/74 ; C07D207/24 ; A61P17/10 ; A61P17/06 ; A61P35/02 ; A61P17/02

Abstract:
This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a dimethyl-nonatetraenyl-trimethyl-cyclohexyl structure useful as therapeutics for the treatment of subjects suffering from disorders characterized by abnormal proliferation and/or abnormal differentiation of cells, in particular of cells of which the growth and differentiation is sensitive to the actions of retinoids.
Public/Granted literature
- US20180339961A1 DIMETHYL-NONATETRAENYL-TRIMETHYL-CYCLOHEXYL COMPOUNDS AND USES THEREOF Public/Granted day:2018-11-29
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