- 专利标题： Antagonists of the muscarinic acetylcholine receptor M4
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申请号： US16756430申请日： 2018-10-17
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公开(公告)号： US11149022B2公开(公告)日： 2021-10-19
- 发明人: Craig W. Lindsley , P. Jeffrey Conn , Darren W. Engers , Aaron M. Bender , Julie L. Engers
- 申请人： Vanderbilt University
- 申请人地址： US TN Nashville
- 专利权人： Vanderbilt University
- 当前专利权人： Vanderbilt University
- 当前专利权人地址： US TN Nashville
- 代理机构： Michael Best & Friedrich LLP
- 国际申请： PCT/US2018/056233 WO 20181017
- 国际公布： WO2019/079410 WO 20190425
- 主分类号： C07D401/14
- IPC分类号： C07D401/14 ; C07D401/12 ; C07D409/14 ; C07D405/14
摘要：
Disclosed herein are substituted 7-azaspiro[3.5]nonane compounds, which may be useful as antagonists of the muscarinic acetylcholine receptor M4 (mAChR M4). Also disclosed herein are methods of making the compounds, pharmaceutical compositions comprising the compounds, and methods of treating disorders using the compounds and compositions.
公开/授权文献
- US20210188811A1 ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 公开/授权日：2021-06-24
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