Invention Grant
- Patent Title: Antagonists of the muscarinic acetylcholine receptor M4
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Application No.: US16756430Application Date: 2018-10-17
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Publication No.: US11149022B2Publication Date: 2021-10-19
- Inventor: Craig W. Lindsley , P. Jeffrey Conn , Darren W. Engers , Aaron M. Bender , Julie L. Engers
- Applicant: Vanderbilt University
- Applicant Address: US TN Nashville
- Assignee: Vanderbilt University
- Current Assignee: Vanderbilt University
- Current Assignee Address: US TN Nashville
- Agency: Michael Best & Friedrich LLP
- International Application: PCT/US2018/056233 WO 20181017
- International Announcement: WO2019/079410 WO 20190425
- Main IPC: C07D401/14
- IPC: C07D401/14 ; C07D401/12 ; C07D409/14 ; C07D405/14
Abstract:
Disclosed herein are substituted 7-azaspiro[3.5]nonane compounds, which may be useful as antagonists of the muscarinic acetylcholine receptor M4 (mAChR M4). Also disclosed herein are methods of making the compounds, pharmaceutical compositions comprising the compounds, and methods of treating disorders using the compounds and compositions.
Public/Granted literature
- US20210188811A1 ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 Public/Granted day:2021-06-24
Information query
