- 专利标题： Heteroaryl compound, enantiomer, diastereomer or pharmaceutically acceptable salt thereof, and antiviral composition containing same as active ingredient
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申请号： US16338237申请日： 2017-09-29
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公开(公告)号： US11149033B2公开(公告)日： 2021-10-19
- 发明人: Ji Young Min , So Young Chang , Ji Hye Lee , Sun Hee Kang , Sun Ju Kong , Su Yeon Jo , Young Mi Kim , Junghwan Choi
- 申请人： INSTITUT PASTEUR KOREA , ST PHARM CO., LTD.
- 申请人地址： KR Gyeonggi-do; KR Gyeonggi-do
- 专利权人： INSTITUT PASTEUR KOREA,ST PHARM CO., LTD.
- 当前专利权人： INSTITUT PASTEUR KOREA,ST PHARM CO., LTD.
- 当前专利权人地址： KR Gyeonggi-do; KR Gyeonggi-do
- 代理机构： Harness, Dickey & Pierce, P.L.C.
- 优先权： KR10-2016-0126997 20160930
- 国际申请： PCT/KR2017/011091 WO 20170929
- 国际公布： WO2018/062978 WO 20180405
- 主分类号： C07D413/06
- IPC分类号： C07D413/06 ; C07D263/46 ; C07D271/10 ; C07D271/113 ; C07D307/64 ; C07D405/06
摘要：
The present invention relates to a novel heteroaryl compound, an enantiomer, a diastereomer or a pharmaceutically acceptable salt thereof, and an antiviral composition comprising the same as an active ingredient. The novel compounds represented by formula (I) or formula (II) according to the present invention are remarkably superior in antiviral activity against an influenza virus, and furthermore, have low cytotoxicity and thus low adverse effects on a human body. Therefore, a pharmaceutical composition containing the same as an active ingredient can be effectively used for the prevention or treatment of diseases caused by an influenza virus infection.
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