Invention Grant
- Patent Title: Fused triazole agonists of the APJ receptor
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Application No.: US16760947Application Date: 2018-10-25
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Publication No.: US11149040B2Publication Date: 2021-10-19
- Inventor: Paul John Dransfield , James S. Harvey , Zhihua Ma , Ankit Sharma
- Applicant: AMGEN INC.
- Applicant Address: US CA Thousand Oaks
- Assignee: AMGEN INC.
- Current Assignee: AMGEN INC.
- Current Assignee Address: US CA Thousand Oaks
- Agency: Fenwick & West LLP
- International Application: PCT/US2018/057466 WO 20181025
- International Announcement: WO2019/089335 WO 20190509
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C07D498/04 ; C07D498/14 ; A61K31/395 ; A61K31/553 ; A61P9/00 ; C07F7/08 ; A61K45/06

Abstract:
Compounds of Formula I, pharmaceutically acceptable salts thereof, tautomers thereof, pharmaceutically acceptable salts of the tautomers, or mixtures thereof are agonists of the APJ Receptor and may have use in treating cardiovascular and other conditions. Compounds of Formula (I) have the following structure: where the definitions of the variables are provided herein.
Public/Granted literature
- US20200308189A1 FUSED TRIAZOLE AGONISTS OF THE APJ RECEPTOR Public/Granted day:2020-10-01
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