A driving circuit, a display apparatus and a driving method thereof are provided. The display panel is divided into a plurality of regions including a first region having a rectangular form and a second region having a free form. The driving circuit generates a plurality of control clocks having a first duty cycle during a first period and a second duty cycle different from the first duty cycle during a second period, or having a first phase shift during the first period and a second phase shift different from the first phase shift during the second period, or having a first driving capability during the first period and a second driving capability different from the first driving capability during the second period. Wherein, the control clocks are configured to be transmitted to a gate driving circuit disposed on the display panel for generating a first plurality of scan signals controlling the first region and a second plurality of scan signals controlling the second region according to the control clocks, so as to reduce a luminance difference between the first region and the second region.