Provided is a vacuum insulation glass panel assembly manufacturing method and apparatus. The vacuum insulation glass panel assembly manufacturing method includes an edge sealing step of sealing an edge of a glass panel assembly of glass panels spaced apart at a predetermined interval, and an exhaust port sealing step of causing a lid member to seal an exhaust port of the glass panel assembly formed so as to communicate with a space between the glass panels whose edges are sealed. A glass solder having a high melting point is used in the edge sealing step, and a glass solder having a low melting point is used in the exhaust port sealing step. A specially designed lid member closing device is used for exhaust port sealing.