- 专利标题： Compositions and methods for tagging ribonucleic acids
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申请号： US16526835申请日： 2019-07-30
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公开(公告)号： US11155821B2公开(公告)日： 2021-10-26
- 发明人: Amy E. Palmer , Esther Braselmann , Robert T. Batey , Dorota Gryko
- 申请人： The Regents of the University of Colorado, a body corporate , Institute of Organic Chemistry POS
- 申请人地址： US CO Denver; PL Warsaw
- 专利权人： The Regents of the University of Colorado, a body corporate,Institute of Organic Chemistry POS
- 当前专利权人： The Regents of the University of Colorado, a body corporate,Institute of Organic Chemistry POS
- 当前专利权人地址： US CO Denver; PL Warsaw
- 代理机构： Medlen & Carroll, LLP
- 主分类号： C12N15/115
- IPC分类号： C12N15/115 ; C12Q1/68
摘要：
This invention relates to the field of ribonucleic acid (RNA) regulation of intracellular activity. In particular, the invention relates to compositions and methods of identifying and tracking specific intracellular RNAs. For example, a fluorescently tagged RNA probe may be tracked by in vivo live imaging throughout its intracellular lifetime in order to determine its purpose and identify regulatory targets to modify its effects. Alternatively, an RNA probe may carry a therapeutic payload for treatment of medical condition or disorder.
公开/授权文献
- US20200149046A1 Compositions and Methods for Tagging Ribonucleic Acids 公开/授权日：2020-05-14
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