Invention Grant
![Pyrrolo[2,3-C]pyridines and related analogs as LSD-1 inhibitors](/docs/US/2021-11-09/US11168082B2/abs.jpg.600x600.jpg)
- Patent Title: Pyrrolo[2,3-C]pyridines and related analogs as LSD-1 inhibitors
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Application No.: US16611238Application Date: 2018-05-15
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Publication No.: US11168082B2Publication Date: 2021-11-09
- Inventor: Shaomeng Wang , Dengyou Zhang , Canhui Zheng , Zhuo Chen , Liu Liu , Liyue Huang , Chao-Yie Yang
- Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- Applicant Address: US MI Ann Arbor
- Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- Current Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- Current Assignee Address: US MI Ann Arbor
- Agency: Marshall, Gerstein & Borun LLP
- International Application: PCT/US2018/032619 WO 20180515
- International Announcement: WO2018/213211 WO 20181122
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61P35/00 ; C07D519/00
![Pyrrolo[2,3-C]pyridines and related analogs as LSD-1 inhibitors](/abs-image/US/2021/11/09/US11168082B2/abs.jpg.150x150.jpg)
Abstract:
The present disclosure provides compounds represented by Formula I and II: and the pharmaceutically acceptable salts and solvates thereof, wherein R1, R2, R3, X, W, Y, and Z are as defined as set forth in the specification. The present disclosure also provides compounds of Formula I and II for use to treat a condition or disorder responsive to LSD1 inhibition such as cancer.
Public/Granted literature
- US20200157091A1 PYRROLO[2,3-C]PYRIDINES AND RELATED ANALOGS AS LSD-1 INHIBITORS Public/Granted day:2020-05-21
Information query
